Phase I study of the safety and pharmacokinetics of trabectedin with docetaxel in patients with advanced malignancies Academic Article uri icon

Overview

MeSH Major

  • Antineoplastic Combined Chemotherapy Protocols
  • Dioxoles
  • Neoplasms
  • Taxoids
  • Tetrahydroisoquinolines

abstract

  • In patients with previously treated, advanced malignancies, the combination of therapeutic doses of trabectedin and docetaxel showed clinical activity and was tolerable with prophylactic G-CSF, with no evidence of clinically important drug interactions.

publication date

  • May 2015

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC4978949

Digital Object Identifier (DOI)

  • 10.1007/s00280-015-2705-z

PubMed ID

  • 25791363

Additional Document Info

start page

  • 1047

end page

  • 55

volume

  • 75

number

  • 5