Detection of rheumatoid arthritis-interstitial lung disease is enhanced by serum biomarkers Academic Article uri icon

Overview

MeSH Major

  • Arthritis, Rheumatoid
  • Lung Diseases, Interstitial

abstract

  • Clinical risk factors and autoantibodies are strongly associated with the presence of clinically evident and subclinical RA-ILD on computed tomography scan in two independent RA cohorts. A biomarker signature composed of matrix metalloproteinase 7, pulmonary and activation-regulated chemokine, and surfactant protein D significantly strengthens this association. These findings may facilitate identification of RA-ILD at an earlier stage, potentially leading to decreased morbidity and mortality.

publication date

  • January 2015

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC4476561

Digital Object Identifier (DOI)

  • 10.1164/rccm.201411-1950OC

PubMed ID

  • 25822095

Additional Document Info

start page

  • 1403

end page

  • 12

volume

  • 191

number

  • 12