Structure-guided blockade of CSF1R kinase in tenosynovial giant-cell tumor Academic Article uri icon

Overview

MeSH Major

  • Aminopyridines
  • Giant Cell Tumors
  • Pyrroles
  • Receptor, Macrophage Colony-Stimulating Factor
  • Soft Tissue Neoplasms

abstract

  • Treatment of tenosynovial giant-cell tumors with PLX3397 resulted in a prolonged regression in tumor volume in most patients. (Funded by Plexxikon; ClinicalTrials.gov number, NCT01004861.).

authors

publication date

  • January 2015

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1056/NEJMoa1411366

PubMed ID

  • 26222558

Additional Document Info

start page

  • 428

end page

  • 37

volume

  • 373

number

  • 5