Late Relapse of Testicular Germ Cell Tumors Review uri icon

Overview

MeSH Major

  • Antineoplastic Combined Chemotherapy Protocols
  • Lymph Nodes
  • Neoplasm Recurrence, Local
  • Neoplasms, Germ Cell and Embryonal
  • Retroperitoneal Space
  • Testicular Neoplasms

abstract

  • Germ cell tumors of the testis have an overall survival rate greater than 90% as a result of a successful multidisciplinary approach to management. Late relapse affects a subset of patients however, and tends to be chemorefractory and the overall prognosis is poor. Surgery is the mainstay in management of late relapse but salvage chemotherapy can be successful. In this review, the clinical presentation and detection of late relapse, clinical outcomes, and predictors of survival in late relapse and the importance of a multidisciplinary treatment approach for successful management of late relapse are discussed.

publication date

  • January 2015

Research

keywords

  • Review

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1016/j.ucl.2015.04.010

PubMed ID

  • 26216823

Additional Document Info

start page

  • 359

end page

  • 68

volume

  • 42

number

  • 3