Prevalence of cerebral amyloid pathology in persons without dementia: A meta-analysis Review uri icon

Overview

MeSH Major

  • Amyloid beta-Peptides
  • Apolipoprotein E4
  • Brain
  • Cognitive Dysfunction

abstract

  • Among persons without dementia, the prevalence of cerebral amyloid pathology as determined by positron emission tomography or cerebrospinal fluid findings was associated with age, APOE genotype, and presence of cognitive impairment. These findings suggest a 20- to 30-year interval between first development of amyloid positivity and onset of dementia.

authors

publication date

  • May 19, 2015

Research

keywords

  • Review

Identity

Language

  • eng

PubMed Central ID

  • PMC4486209

Digital Object Identifier (DOI)

  • 10.1001/jama.2015.4668

PubMed ID

  • 25988462

Additional Document Info

start page

  • 1924

end page

  • 38

volume

  • 313

number

  • 19