Haemophagocytic lymphohistiocytosis in inflammatory bowel disease with virus infection Review uri icon

Overview

MeSH Major

  • Intestinal Diseases
  • Intestines
  • Metagenome
  • Probiotics

abstract

  • © 2015, Termedia Publishing House Ltd. All rights reserved. Patients with inflammatory bowel disease (IBD) are at risk of developing haemophagocytic lymphohistiocytosis (HLH) because of chronic systemic inflammation as well as exposure to immunosuppressive medications. The two main causes of HLH in IBD patients are infection with cytomegalovirus and Epstein-Barr virus. Patients with Crohn's disease are more susceptible to HLH than those with ulcerative colitis. The majority of cases are seen in people receiving an immunosuppressive regimen that included thiopurines.

publication date

  • January 2015

Research

keywords

  • Review

Identity

Language

  • eng

PubMed Central ID

  • PMC4631275

Digital Object Identifier (DOI)

  • 10.5114/pg.2015.48995

PubMed ID

  • 26557937

Additional Document Info

start page

  • 78

end page

  • 82

volume

  • 10

number

  • 2