Effective treatment of diverse medulloblastoma models with mebendazole and its impact on tumor angiogenesis Academic Article uri icon

Overview

MeSH Major

  • Antineoplastic Agents
  • Cerebellar Neoplasms
  • Mebendazole
  • Medulloblastoma
  • Neovascularization, Pathologic

abstract

  • Our findings support testing of MBZ as a possible low-toxicity therapy for medulloblastomas of various molecular subtypes, including tumors with acquired vismodegib resistance. Its antitumor mechanism may be partially explained by inhibition of tumor angiogenesis.

publication date

  • January 2015

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC4483072

Digital Object Identifier (DOI)

  • 10.1093/neuonc/nou234

PubMed ID

  • 25253417

Additional Document Info

start page

  • 545

end page

  • 54

volume

  • 17

number

  • 4