Pretreatment Dynamic Susceptibility Contrast MRI Perfusion in Glioblastoma: Prediction of EGFR Gene Amplification Academic Article uri icon

Overview

MeSH Major

  • Brain Neoplasms
  • Contrast Media
  • Gene Amplification
  • Glioblastoma
  • Image Interpretation, Computer-Assisted
  • Magnetic Resonance Angiography
  • Receptor, Epidermal Growth Factor

abstract

  • DSC MRI perfusion may have a role in identifying patients with EGFR gene amplification and EGFRvIII gene mutation status, potential targets for individualized treatment protocols. Our results raise the need for further investigation for imaging biomarkers of genetically unique GBM subtypes.

publication date

  • January 29, 2014

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC4712066

Digital Object Identifier (DOI)

  • 10.1007/s00062-014-0289-3

PubMed ID

  • 24474262

Additional Document Info

start page

  • 143

end page

  • 50

volume

  • 25

number

  • 2