Measuring social communication behaviors as a treatment endpoint in individuals with autism spectrum disorder. Review uri icon

Overview

MeSH

  • Humans
  • Reproducibility of Results
  • Social Behavior
  • Treatment Outcome

MeSH Major

  • Autism Spectrum Disorder
  • Communication
  • Outcome Assessment (Health Care)
  • Psychometrics
  • Social Perception
  • Social Skills

abstract

  • Social communication impairments are a core deficit in autism spectrum disorder. Social communication deficit is also an early indicator of autism spectrum disorder and a factor in long-term outcomes. Thus, this symptom domain represents a critical treatment target. Identifying reliable and valid outcome measures for social communication across a range of treatment approaches is essential. Autism Speaks engaged a panel of experts to evaluate the readiness of available measures of social communication for use as outcome measures in clinical trials. The panel held monthly conference calls and two face-to-face meetings over 14 months. Key criteria used to evaluate measures included the relevance to the clinical target, coverage of the symptom domain, and psychometric properties (validity and reliability, as well as evidence of sensitivity to change). In all, 38 measures were evaluated and 6 measures were considered appropriate for use, with some limitations. This report discusses the relative strengths and weaknesses of existing social communication measures for use in clinical trials and identifies specific areas in need of further development. © The Author(s) 2014.

publication date

  • July 2015

has subject area

  • Autism Spectrum Disorder
  • Communication
  • Humans
  • Outcome Assessment (Health Care)
  • Psychometrics
  • Reproducibility of Results
  • Social Behavior
  • Social Perception
  • Social Skills
  • Treatment Outcome

Research

keywords

  • Journal Article
  • Review

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1177/1362361314542955

PubMed ID

  • 25096930

Additional Document Info

start page

  • 622

end page

  • 636

volume

  • 19

number

  • 5