Quantitative apparent diffusion coefficient (ADC) values as an imaging biomarker for fibrosis in pediatric Crohn’s disease: preliminary experience Academic Article uri icon

Overview

MeSH Major

  • Crohn Disease
  • Diffusion Magnetic Resonance Imaging

abstract

  • Quantitative ADC measures of transmural fibrosis are lower compared to the reported values of inflammation in Crohn's disease. To our knowledge, this is the first pediatric pilot study to investigate the correlation of quantitative DWI with histology of surgical specimens in pediatric patients with Crohn's disease. Our results are comparable to a recently published study in adult Crohn's patients showing a significant correlation between a decrease in ADC values and fibrosis.

publication date

  • September 24, 2015

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1007/s00261-014-0247-1

PubMed ID

  • 25248794

Additional Document Info

start page

  • 1068

end page

  • 74

volume

  • 40

number

  • 5