Estrogens and their precursors in postmenopausal women with early breast cancer receiving anastrozole Academic Article uri icon

Overview

MeSH Major

  • Breast Neoplasms
  • Estrogens
  • Nitriles
  • Postmenopause
  • Triazoles

abstract

  • We demonstrated large inter-individual variability in anastrozole and anastrozole metabolite concentrations as well as E1, E2, E1-C, A, and T concentrations before and while on anastrozole. These findings suggest that the standard 1mg daily dose of anastrozole is not optimal for a substantial proportion of women with breast cancer.

publication date

  • May 26, 2015

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC4339673

Digital Object Identifier (DOI)

  • 10.1016/j.steroids.2014.08.007

PubMed ID

  • 25163006

Additional Document Info

start page

  • 32

end page

  • 8

number

  • Part A