The safety and efficacy of single-agent pemetrexed in platinum-resistant advanced urothelial carcinoma: A large single-institution experience Academic Article uri icon

Overview

MeSH Major

  • Carcinoma, Transitional Cell
  • Drug Resistance, Neoplasm
  • Pemetrexed
  • Urinary Bladder Neoplasms

abstract

  • This 129-patient series is the largest reported data set describing pemetrexed use in advanced UC. Activity was modest, although discovery of molecular biomarkers predictive of response would be valuable to identify the small subset of patients who do gain significant benefit. Overall, the data highlight the urgent need to develop novel therapies for these patients.

publication date

  • January 2015

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC4425381

Digital Object Identifier (DOI)

  • 10.1634/theoncologist.2014-0354

PubMed ID

  • 25845990

Additional Document Info

start page

  • 508

end page

  • 15

volume

  • 20

number

  • 5