Brincidofovir for Polyomavirus-Associated Nephropathy after Allogeneic Hematopoietic Stem Cell Transplantation Academic Article uri icon

Overview

MeSH Major

  • BK Virus
  • Cytomegalovirus Infections
  • Cytosine
  • Hematopoietic Stem Cell Transplantation
  • Kidney Diseases
  • Organophosphonates
  • Polyomavirus Infections
  • Tumor Virus Infections

abstract

  • Polyomavirus-associated nephropathy (PVAN) is common in patients who have undergone kidney transplantation and has been reported in hematopoietic stem cell (HSC) transplant recipients. Aside from reduction of immunosuppression, few therapeutic options exist for treatment of PVAN. We report a case of PVAN in a severely immunocompromised allogeneic HSC transplant recipient that was treated with brincidofovir without reduction of immunosuppression. We review our institutional experience of PVAN in HSC transplantation and discuss the potential use of brincidofovir for treatment.

publication date

  • January 2015

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1053/j.ajkd.2014.11.020

PubMed ID

  • 25600489

Additional Document Info

start page

  • 780

end page

  • 4

volume

  • 65

number

  • 5