Indium 111-labeled J591 anti-PSMA antibody for vascular targeted imaging in progressive solid tumors Academic Article uri icon

Overview

MeSH Major

  • Antigens, Surface
  • Glutamate Carboxypeptidase II
  • Prostatic Neoplasms
  • Radioimmunotherapy

abstract

  • Radiolabeled J591 antibody has potential as a targeting agent for solid tumor vasculature and lesion detection. Bone and soft tissue lesions arising from tumors of diverse origin were targeted by the anti-PSMA antibody J591. For the detection of lesions in these tumors by J591 antibody scans, an antibody mass of 20 mg is adequate. The optimal time of imaging is 5 to 7 days post-injection.

publication date

  • December 12, 2015

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC4425739

Digital Object Identifier (DOI)

  • 10.1186/s13550-015-0104-4

PubMed ID

  • 25984435

Additional Document Info

start page

  • 28

volume

  • 5

number

  • 1