Examining the utility of patient-derived xenograft mouse models Review uri icon

Overview

MeSH Major

  • Neoplasm Transplantation
  • Neoplasms
  • Neoplasms, Experimental
  • Transplantation, Heterologous

abstract

  • Patient-derived xenograft (PDX) models are now being widely used in cancer research and have the potential to greatly inform our understanding of cancer biology. However, many questions remain, especially regarding the ability of PDX models to affect clinical decision making. With these points in mind, we asked three scientists to give their opinions on the generation and uses of PDX models and the future of this field.

publication date

  • January 2015

Research

keywords

  • Review

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1038/nrc3944

PubMed ID

  • 25907221

Additional Document Info

start page

  • 311

end page

  • 6

volume

  • 15

number

  • 5