Modeling the relationship among gray matter atrophy, abnormalities in connecting white matter, and cognitive performance in early multiple sclerosis Academic Article uri icon

Overview

MeSH Major

  • Brain
  • Gray Matter
  • Models, Neurological
  • Multiple Sclerosis
  • White Matter

abstract

  • We concluded that deep gray matter regions may be susceptible to inflammation and/or demyelination in white matter, possibly having a higher sensitivity to remote degeneration, and that lesions affecting visual processing pathways were related to processing speed. The Network Modification Tool may be used to quantify the impact of early white matter abnormalities on both connecting gray matter structures and processing speed.

publication date

  • April 2015

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC4951088

Digital Object Identifier (DOI)

  • 10.3174/ajnr.A4165

PubMed ID

  • 25414004

Additional Document Info

start page

  • 702

end page

  • 9

volume

  • 36

number

  • 4