Molecular profiling and targeted therapy for advanced thoracic malignancies a biomarker-derived, multiarm, multihistology phase ii basket trial Academic Article uri icon

Overview

MeSH Major

  • Biomarkers, Tumor
  • Carcinoma, Non-Small-Cell Lung
  • Lung Neoplasms
  • Molecular Targeted Therapy
  • Small Cell Lung Carcinoma
  • Thymus Neoplasms

abstract

  • This basket trial design was not feasible for many of the arms with rare mutations, but it allowed the study of the genetics of less common malignancies.

publication date

  • March 20, 2015

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC4356709

Digital Object Identifier (DOI)

  • 10.1200/JCO.2014.58.2007

PubMed ID

  • 25667274

Additional Document Info

start page

  • 1000

end page

  • 7

volume

  • 33

number

  • 9