Pathology of Adenocarcinoma Chapter uri icon


MeSH Major

  • Carcinoma, Large Cell
  • Carcinoma, Small Cell
  • Lung Neoplasms
  • Neuroendocrine Tumors


  • © 2014 John Wiley & Sons, Inc. All rights reserved.This chapter summarizes the pathology of lung adenocarcinoma based on the 2011 IASLC/ATS/ERS classification. This has resulted in major changes including: (1) new concepts of AIS and minimally invasive adenocarcinoma (MIA) have been introduced; (2) the term bronchioloalveolar carcinoma (BAC) is no longer used as tumors formerly classified under this term fall into five different places in this classification; (3) invasive adenocarcinomas are evaluated using comprehensive histologic subtyping with subtyping according to the predominant subtype; (4) the term lepidic predominant adenocarcinoma is used for tumors previously classified as "mixed subtype" adenocarcinoma with a predominant component formerly called nonmucinous BAC and the term "mixed subtype" is discontinued; (5) the micropapillary pattern is introduced as a new subtype with a poor prognosis; (6) tumors previously classified as mucinous BAC are now classified as invasive mucinous adenocarcinoma. An entirely new aspect of lung cancer diagnosis in small biopsies and cytology is now addressed.

publication date

  • May 27, 2014



  • Book Chapter


Digital Object Identifier (DOI)

  • 10.1002/9781118468791.ch8

Additional Document Info

start page

  • 144

end page

  • 157