Gene expression profiling of lobular carcinoma in situ reveals candidate precursor genes for invasion Academic Article uri icon

Overview

MeSH Major

  • Breast Neoplasms
  • Carcinoma in Situ
  • Carcinoma, Lobular
  • Gene Expression Profiling
  • Gene Expression Regulation, Neoplastic
  • Genetic Association Studies
  • Neoplasm Invasiveness

abstract

  • Here we demonstrate that classic LCIS is a heterogeneous disease at the transcriptomic level and identify potential precursor genes in lobular carcinogenesis. Understanding the molecular heterogeneity of LCIS and the potential role of these potential precursor genes may help personalize the therapy of patients with LCIS.

publication date

  • January 2015

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC4387062

Digital Object Identifier (DOI)

  • 10.1016/j.molonc.2014.12.005

PubMed ID

  • 25601220

Additional Document Info

start page

  • 772

end page

  • 82

volume

  • 9

number

  • 4