Gene expression profiling of lobular carcinoma in situ reveals candidate precursor genes for invasion
Carcinoma in Situ
Gene Expression Profiling
Gene Expression Regulation, Neoplastic
Genetic Association Studies
Here we demonstrate that classic LCIS is a heterogeneous disease at the transcriptomic level and identify potential precursor genes in lobular carcinogenesis. Understanding the molecular heterogeneity of LCIS and the potential role of these potential precursor genes may help personalize the therapy of patients with LCIS.