β-1 tubulin R307H SNP alters microtubule dynamics and affects severity of a hereditary thrombocytopenia Academic Article uri icon

Overview

MeSH Major

  • Bernard-Soulier Syndrome
  • Blood Platelets
  • Microtubules
  • Polymorphism, Single Nucleotide
  • Tubulin

abstract

  • Our data show that the R307H SNP is significantly associated with the degree of thrombocytopenia in congenital and acquired platelet disorders, and may affect platelets by altering microtubule behavior.

publication date

  • January 2015

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1111/jth.12824

PubMed ID

  • 25529050

Additional Document Info

start page

  • 651

end page

  • 9

volume

  • 13

number

  • 4