Risk of revision following total hip arthroplasty: Metal-on-conventional polyethylene compared with metal-on-highly cross-linked polyethylene bearing surfaces: International results from six registries Academic Article uri icon


MeSH Major

  • Arthroplasty, Replacement, Hip
  • Hip Prosthesis
  • Osteoarthritis, Hip
  • Prosthesis Design


  • The results of randomized controlled trials and systematic reviews have suggested reduced radiographic wear in highly cross-linked polyethylene compared with conventional polyethylene in primary total hip arthroplasty. However, longer-term clinical results have not been thoroughly examined, to our knowledge. The purpose of this study was to compare the risk of revision for metal-on-conventional and metal-on-highly cross-linked total hip arthroplasty bearing surfaces with use of a distributed data network of six national and regional registries (Kaiser Permanente, HealthEast, the Emilia-Romagna region in Italy, the Catalan region in Spain, Norway, and Australia). Inclusion criteria were osteoarthritis as the primary diagnosis, cementless implant fixation, and a patient age of forty-five to sixty-four years. These criteria resulted in a sample of 16,571 primary total hip arthroplasties. Multivariate meta-analysis was performed with use of linear mixed models, with survival probability as the unit of analysis. The results of a fixed-effects model suggested that there was insufficient evidence of a difference in risk of revision between bearing surfaces (hazard ratio, 1.20 [95% confidence interval, 0.80 to 1.79]; p = 0.384). Highly cross-linked polyethylene does not appear to have a reduced risk of revision in this subgroup of total hip arthroplasty patients. Arthroplasties involving highly cross-linked polyethylene do not appear to have an increased risk of revision in this subgroup of total hip arthroplasty patients.

publication date

  • January 2014



  • Academic Article



  • eng

PubMed Central ID

  • PMC4271419

Digital Object Identifier (DOI)

  • 10.2106/JBJS.N.00460

PubMed ID

  • 25520415

Additional Document Info

start page

  • 19

end page

  • 24


  • 96