Peripheral CD5+ B cells in antineutrophil cytoplasmic antibody-associated vasculitis Academic Article uri icon

Overview

MeSH Major

  • Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
  • Antigens, CD5
  • Antirheumatic Agents
  • B-Lymphocytes

abstract

  • The percentage of peripheral CD5+ B cells might reflect disease activity in RTX-treated patients. However, sole staining for CD5 as a putative surrogate marker for Breg cells did not identify a subpopulation of B cells with clear potential for meaningful clinical use. Adequate phenotyping of Breg cells is required to further explore the value of these cells as biomarkers in AAV.

publication date

  • January 2015

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC4497572

Digital Object Identifier (DOI)

  • 10.1002/art.38916

PubMed ID

  • 25332071

Additional Document Info

start page

  • 535

end page

  • 44

volume

  • 67

number

  • 2