Clinical characteristics and course of 63 patients with BRAF mutant lung cancers Academic Article uri icon

Overview

MeSH Major

  • Carcinoma, Non-Small-Cell Lung
  • Lung Neoplasms
  • Mutation
  • Proto-Oncogene Proteins B-raf

abstract

  • This is the largest series of patients with BRAF mutant lung cancers described. Most patients were heavy smokers. Nineteen percent of patients with early-stage BRAF mutant lung cancers developed second primary lung cancers harboring KRAS mutations. Patients with advanced lung adenocarcinomas harboring V600 mutations have an improved OS compared with those with non-V600 mutations.

publication date

  • January 2014

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC4251710

Digital Object Identifier (DOI)

  • 10.1097/JTO.0000000000000344

PubMed ID

  • 25436800

Additional Document Info

start page

  • 1669

end page

  • 74

volume

  • 9

number

  • 11