Clinical characteristics and course of 63 patients with BRAF mutant lung cancers
Carcinoma, Non-Small-Cell Lung
Proto-Oncogene Proteins B-raf
This is the largest series of patients with BRAF mutant lung cancers described. Most patients were heavy smokers. Nineteen percent of patients with early-stage BRAF mutant lung cancers developed second primary lung cancers harboring KRAS mutations. Patients with advanced lung adenocarcinomas harboring V600 mutations have an improved OS compared with those with non-V600 mutations.