Acetate fuels the cancer engine Academic Article uri icon

Overview

MeSH Major

  • Phosphatidylinositol 3-Kinases

abstract

  • Cancer cells have distinctive nutrient demands to fuel growth and proliferation, including the disproportionate use of glucose, glutamine, and fatty acids. Comerford et al. and Mashimo et al. now demonstrate that several types of cancer are avid consumers of acetate, which facilitates macromolecular biosynthesis and histone modification.

publication date

  • December 18, 2014

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1016/j.cell.2014.12.009

PubMed ID

  • 25525870

Additional Document Info

start page

  • 1492

end page

  • 4

volume

  • 159

number

  • 7