Emerging therapies for glioblastoma Review uri icon

Overview

MeSH Major

  • Brain Neoplasms
  • Cell- and Tissue-Based Therapy
  • Dacarbazine
  • Glioblastoma
  • Immunotherapy

abstract

  • Glioblastoma is an aggressive tumor with heterogeneous molecular features and complex host interactions, many of which are amenable to therapeutic intervention. Meaningful treatment advances will depend on identifying agents that target mechanistic vulnerabilities that are relevant to specific subgroups of patients; increasing patient enrollment into clinical trials is essential to accelerate the development of patient-tailored treatments.

publication date

  • January 2014

Research

keywords

  • Review

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1001/jamaneurol.2014.1701

PubMed ID

  • 25244650

Additional Document Info

start page

  • 1437

end page

  • 44

volume

  • 71

number

  • 11