Vasculitis in antiphospholipid syndrome Review uri icon

Overview

MeSH Major

  • Antiphospholipid Syndrome
  • Hemorrhage
  • Livedo Reticularis
  • Lung Diseases
  • Retinal Vasculitis
  • Thrombosis

abstract

  • The major manifestations of antiphospholipid syndrome (APS) are caused by thrombosis within the venous or arterial vasculature, whereas the vascular lesions in systemic vasculitis result from an inflammatory infiltrate in the vessel wall. There is an association between vascular thrombosis and inflammation, however, as vasculitis can occur in APS and thromboembolic complications are seen in systemic vasculitis. Although differentiating between vasculitis and antiphospholipid-associated thrombosis can be difficult, it may be crucial to do so given the different therapeutic implications for immunosuppression or anticoagulation. This article explores the relationship between thrombosis and inflammation as it relates to APS and systemic vasculitis.

publication date

  • January 2015

Research

keywords

  • Review

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1016/j.rdc.2014.09.009

PubMed ID

  • 25399943

Additional Document Info

start page

  • 109

end page

  • 23, ix

volume

  • 41

number

  • 1