An evaluation of deficits in semantic cueing and proactive and retroactive interference as early features of Alzheimer's disease Academic Article uri icon


MeSH Major

  • Alzheimer Disease
  • Cognitive Dysfunction
  • Memory Disorders
  • Mental Recall
  • Neuropsychological Tests
  • Predictive Value of Tests
  • Semantics


  • The LASSI-L paradigm is unique and unlike other assessments of memory in that items posed for cued recall are explicitly presented, and semantic interference and cueing effects can be assessed while controlling for initial level of memory impairment. This is a powerful procedure that allows the participant to serve as his or her own control. The high levels of discrimination between subjects with aMCI and normal cognition that exceeded traditional neuropsychological measures makes the LASSI-L worthy of further research in the detection of early AD.

publication date

  • January 2014



  • Academic Article



  • eng

PubMed Central ID

  • PMC4668200

Digital Object Identifier (DOI)

  • 10.1016/j.jagp.2013.01.066

PubMed ID

  • 23768680

Additional Document Info

start page

  • 889

end page

  • 97


  • 22


  • 9