The effects of soy supplementation on gene expression in breast cancer: a randomized placebo-controlled study. Academic Article uri icon

Overview

MeSH Major

  • Breast Neoplasms
  • Carcinoma, Ductal, Breast
  • Dietary Supplements
  • Genistein
  • Receptor, Fibroblast Growth Factor, Type 2
  • Soybean Proteins

abstract

  • Gene expression associated with soy intake and high plasma genistein defines a signature characterized by overexpression of FGFR2 and genes that drive cell cycle and proliferation pathways. These findings raise the concerns that in a subset of women soy could adversely affect gene expression in breast cancer.

publication date

  • January 2014

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC4817128

PubMed ID

  • 25190728

Additional Document Info

volume

  • 106

number

  • 9