US lung cancer trends by histologic type Academic Article uri icon

Overview

MeSH Major

  • Adenocarcinoma
  • Carcinoma, Large Cell
  • Carcinoma, Small Cell
  • Carcinoma, Squamous Cell
  • Lung Neoplasms

abstract

  • US lung cancer trends vary by sex, histologic type, racial/ethnic group, and age, reflecting historical cigarette smoking rates, duration, cessation, cigarette composition, and exposure to other carcinogens. Substantial excesses among males have diminished and higher rates of adenocarcinoma among young females have emerged as rates among males declined more rapidly. The recognition of EGFR mutation and ALK rearrangements that occur primarily in adenocarcinomas are the primary basis for the molecular revolution that has transformed lung cancer diagnosis and treatment over the past decade, and these changes have affected recent type-specific trends.

publication date

  • January 2014

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC4187244

Digital Object Identifier (DOI)

  • 10.1002/cncr.28749

PubMed ID

  • 25113306

Additional Document Info

start page

  • 2883

end page

  • 92

volume

  • 120

number

  • 18