Accurate identification of ALK positive lung carcinoma patients: Novel FDA-cleared automated fluorescence in situ hybridization scanning system and ultrasensitive immunohistochemistry Academic Article uri icon

Overview

MeSH Major

  • Carcinoma, Non-Small-Cell Lung
  • Immunohistochemistry
  • In Situ Hybridization, Fluorescence
  • Lung Neoplasms
  • Receptor Protein-Tyrosine Kinases

abstract

  • The specificity of these ultrasensitive IHC assays may obviate the need for FISH confirmation in positive IHC cases. However, the likelihood of false negative IHC results strengthens the case for FISH testing, at least in some situations.

publication date

  • September 23, 2014

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC4172507

Digital Object Identifier (DOI)

  • 10.1371/journal.pone.0107200

PubMed ID

  • 25248157

Additional Document Info

start page

  • e107200

volume

  • 9

number

  • 9