Discovery of Biomarkers Predictive of GSI Response in Triple-Negative Breast cancer and Adenoid Cystic carcinoma Academic Article uri icon

Overview

MeSH Major

  • Amyloid Precursor Protein Secretases
  • Antineoplastic Agents
  • Carcinoma, Adenoid Cystic
  • Protease Inhibitors
  • Triple Negative Breast Neoplasms

abstract

  • NOTCH1 mutations, immunohistochemical staining for activated NOTCH1, and HES4 expression are biomarkers that can be used to identify solid tumors that are likely to respond to GSI-based therapies.

publication date

  • January 2014

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC4184927

Digital Object Identifier (DOI)

  • 10.1158/2159-8290.CD-13-0830

PubMed ID

  • 25104330

Additional Document Info

start page

  • 1154

end page

  • 67

volume

  • 4

number

  • 10