Genetic/familial high-risk assessment: Breast and ovarian, version 1.2014 Review uri icon

Overview

MeSH Major

  • Hamartoma Syndrome, Multiple

abstract

  • During the past few years, several genetic aberrations that may contribute to increased risks for development of breast and/or ovarian cancers have been identified. The NCCN Guidelines for Genetic/Familial High-Risk Assessment: Breast and Ovarian focus specifically on the assessment of genetic mutations in BRCA1/BRCA2, TP53, and PTEN, and recommend approaches to genetic testing/counseling and management strategies in individuals with these mutations. This portion of the NCCN Guidelines includes recommendations regarding diagnostic criteria and management of patients with Cowden Syndrome/PTEN hamartoma tumor syndrome.

publication date

  • January 2014

Research

keywords

  • Review

Identity

Language

  • eng

PubMed ID

  • 25190698

Additional Document Info

start page

  • 1326

end page

  • 38

volume

  • 12

number

  • 9