Impairment of high-density lipoprotein resistance to lipid peroxidation and adipose tissue inflammation in obesity complicated by obstructive sleep apnea Academic Article uri icon

Overview

MeSH Major

  • Adipose Tissue
  • Lipid Peroxidation
  • Lipoproteins, HDL
  • Obesity, Morbid
  • Panniculitis
  • Sleep Apnea, Obstructive

abstract

  • Increased serum TNFα, ICAM-1, and TNFα expression in SAT provide a mechanistic basis for enhanced inflammation in patients with OSA. Decreased serum PON1 activity, impaired HDL antioxidant function, and increased adipose tissue inflammation in these patients could be a mechanism for HDL and endothelial dysfunction.

publication date

  • January 2014

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1210/jc.2013-3939

PubMed ID

  • 24823455

Additional Document Info

start page

  • 3390

end page

  • 8

volume

  • 99

number

  • 9