Portal, superior mesenteric and splenic vein thrombosis secondary to hyperhomocysteinemia with pernicious anemia: A case report Academic Article uri icon

Overview

MeSH Major

  • Anemia, Pernicious
  • Hyperhomocysteinemia
  • Venous Thrombosis

abstract

  • This report demonstrates that pernicious anemia, on its own, can lead to hyperhomocysteinemia significant enough to lead to lethal multiple splanchnic vein thrombosis. Our case also underscores the need to (1) consider portomesenteric thrombosis in the differential diagnosis of epigastric abdominal pain, (2) perform a complete thrombotic work-up to elucidate metabolic abnormalities that could be contributing to a pro-thrombotic state and (3) initiate aggressive measures, including early consideration of multi-visceral transplantation, in order to avoid decompensation and a significant adverse outcome.

publication date

  • August 25, 2014

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC4154050

Digital Object Identifier (DOI)

  • 10.1186/1752-1947-8-286

PubMed ID

  • 25155131

Additional Document Info

start page

  • 286

volume

  • 8

number

  • 1