Patient-derived Xenograft models: An emerging platform for translational cancer research Review uri icon

Overview

MeSH Major

  • Disease Models, Animal
  • Heterografts
  • Neoplasms
  • Translational Medical Research

abstract

  • PDX models are increasingly used in translational cancer research. These models are useful for drug screening, biomarker development, and the preclinical evaluation of personalized medicine strategies. This review provides a timely overview of the key characteristics of PDX models and a detailed discussion of future directions in the field.

publication date

  • January 2014

Research

keywords

  • Review

Identity

Language

  • eng

PubMed Central ID

  • PMC4167608

Digital Object Identifier (DOI)

  • 10.1158/2159-8290.CD-14-0001

PubMed ID

  • 25185190

Additional Document Info

start page

  • 998

end page

  • 1013

volume

  • 4

number

  • 9