A sustained hypothalamic-pituitary-Adrenal axis response to acute psychosocial stress in irritable bowel syndrome Academic Article uri icon

Overview

MeSH Major

  • Hypothalamo-Hypophyseal System
  • Irritable Bowel Syndrome
  • Pituitary-Adrenal System
  • Stress, Psychological

abstract

  • Patients with IBS exhibit sustained HPA axis activity, and an increase in problematic GI symptoms in response to acute experimental psychosocial stress. These data pave the way for future interventional studies aimed at identifying novel therapeutic approaches to modulate the HPA axis and GI symptom response to acute psychosocial stress in IBS.

publication date

  • January 2014

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1017/S003329171400052X

PubMed ID

  • 25065954

Additional Document Info

start page

  • 3123

end page

  • 34

volume

  • 44

number

  • 14