Targeted prostate cancer screening in BRCA1 and BRCA2 mutation carriers: Results from the initial screening round of the IMPACT study Academic Article uri icon

Overview

MeSH Major

  • Early Detection of Cancer
  • Genes, BRCA1
  • Genes, BRCA2
  • Genetic Predisposition to Disease
  • Mutation
  • Prostate
  • Prostate-Specific Antigen
  • Prostatic Neoplasms

abstract

  • In this report, we demonstrate that germline genetic markers can be used to identify men at higher risk of prostate cancer. Targeting screening at these men resulted in the identification of tumours that were more likely to require treatment.

authors

publication date

  • January 2014

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC4105321

Digital Object Identifier (DOI)

  • 10.1016/j.eururo.2014.01.003

PubMed ID

  • 24484606

Additional Document Info

start page

  • 489

end page

  • 99

volume

  • 66

number

  • 3