BRAF mutation predicts for poor outcomes after metastasectomy in patients with metastatic colorectal cancer Academic Article uri icon

Overview

MeSH Major

  • Colorectal Neoplasms
  • Mutation
  • Proto-Oncogene Proteins B-raf

abstract

  • BRAF-mutant mCRC is associated with worse clinical outcome. Patients with BRAF-mutant tumors more commonly develop peritoneal metastases, less frequently present with disease limited to the liver, and have shorter survival after metastasectomy compared with patients with BRAF wild-type tumors.

publication date

  • August 2014

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC4928876

Digital Object Identifier (DOI)

  • 10.1002/cncr.28729

PubMed ID

  • 24737664

Additional Document Info

start page

  • 2316

end page

  • 24

volume

  • 120

number

  • 15