Muscle dysfunction in cancer patients Review uri icon

Overview

MeSH Major

  • Muscle, Skeletal
  • Neoplasms

abstract

  • There are clear associations between muscle dysfunction and critical clinical end points. Yet there is a discrepancy between timing of exercise intervention trials, which can improve muscle function, and study populations in whom muscle function are proven prognostic important for clinical end points. Thus, future exercise trials should in early-stage patients, be powered to evaluate clinical outcomes associated with improvements in muscle function, or be promoted in advanced stage settings, aiming to reverse cancer-related muscle dysfunction, and thus potentially improve time-to-progression, treatment toxicity and survival.

publication date

  • May 2014

Research

keywords

  • Review

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1093/annonc/mdt551

PubMed ID

  • 24401927

Additional Document Info

start page

  • 947

end page

  • 58

volume

  • 25

number

  • 5