Safety and efficacy of resistance training in germ cell cancer patients undergoing chemotherapy: A randomized controlled trial
Antineoplastic Combined Chemotherapy Protocols
Neoplasms, Germ Cell and Embryonal
BEP was associated with significant reduction in lean mass and strength and trends toward unfavourable changes in muscle fibre size and phenotype composition. Resistance training was safe and attenuated dysfunction in selected endpoints, but BEP blunted several positive adaptations observed in healthy controls. Thus, our study does not support the general application of resistance training in this setting but larger-scaled trials are required to confirm this finding.