ANCA-mediated crescentic glomerulonephritis with linear deposition of IgG along the glomerular basement membrane. Academic Article uri icon

Overview

MeSH Major

  • Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
  • Antibodies, Antineutrophil Cytoplasmic
  • Glomerular Basement Membrane
  • Glomerulonephritis
  • Hemorrhage
  • Immunoglobulin G
  • Lung Diseases

abstract

  • Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitides is an important cause of rapidly progressive glomerulonephritides (RPGN), and they are classically described as pauci-immune diseases as evidenced by the absence of immune deposits on immunofluoresence microscopy of the kidney biopsy. We report two patients with RPGN, pulmonary-renal syndrome, positive ANCA serology and linear Immunoglobulin G (IgG) staining on glomerular basement membrane in the absence of detectable anti-glomerular basement membrane (anti-GBM) antibodies in the serum.

publication date

  • January 2014

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 24821165

Additional Document Info

start page

  • 634

end page

  • 7

volume

  • 25

number

  • 3