Pathologic and molecular features correlate with long-term outcome after adjuvant therapy of resected primary GI stromal tumor: The ACOSOG Z9001 trial Academic Article uri icon

Overview

MeSH Major

  • Benzamides
  • Gastrointestinal Stromal Tumors
  • Mutation
  • Piperazines
  • Proto-Oncogene Proteins c-kit
  • Pyrimidines
  • Receptor, Platelet-Derived Growth Factor alpha

abstract

  • Our findings show that tumor size, location, and mitotic rate, but not tumor genotype, are associated with the natural history of GIST. Patients with KIT exon 11 deletions assigned to 1 year of adjuvant imatinib had a longer RFS.

publication date

  • May 20, 2014

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC4026579

Digital Object Identifier (DOI)

  • 10.1200/JCO.2013.51.2046

PubMed ID

  • 24638003

Additional Document Info

start page

  • 1563

end page

  • 70

volume

  • 32

number

  • 15