CXCR3 controls T-cell accumulation in fat inflammation Academic Article uri icon

Overview

MeSH Major

  • Adipose Tissue
  • Chemotaxis, Leukocyte
  • Obesity
  • Panniculitis
  • Receptors, CXCR3
  • T-Lymphocyte Subsets

abstract

  • These results demonstrate that CXCR3 contributes to T-cell accumulation in periepididymal AT of obese mice. Our results also suggest that CXCR3 regulates the accumulation of distinct subsets of T cells and that the ratio between these functional subsets across time likely modulates local inflammation and systemic metabolism.

publication date

  • January 2014

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC4102314

Digital Object Identifier (DOI)

  • 10.1161/ATVBAHA.113.303133

PubMed ID

  • 24812325

Additional Document Info

start page

  • 1374

end page

  • 81

volume

  • 34

number

  • 7