Diagnostic utility of E-cadherin and P120 catenin cocktail immunostain in distinguishing DCIS from LCIS Academic Article Article uri icon

Overview

MeSH Major

  • Glomerulonephritis, Membranous
  • Graft Rejection
  • Kidney Glomerulus
  • Kidney Transplantation

abstract

  • 1. This antibody cocktail can be applied in daily practice on paraffin-embedded tissue and is especially useful in small biopsies with small foci of CIS lesions. 2. Immunohistochemical staining with the antibody cocktail showed 100% concordance with the traditional single antibody immunostaining using either E-cadherin or P120 catenin antibody. 3. Our antibody cocktail includes E-cadherin as a positive membranous stain for DCIS and P120 catenin as a positive cytoplasmic stain for LCIS, which may enhance accuracy and confidence in the differential diagnoses.

publication date

  • January 2014

Research

keywords

  • Academic Article

Identity

PubMed ID

  • 24966968

Additional Document Info

start page

  • 2551

end page

  • 7

volume

  • 7

number

  • 5