Microfluidic device and culture platform for the observation and control of axonal growth and axonal organelle transport of rat hippocampal neurons Conference Paper uri icon

Overview

MeSH Major

  • Clinical Protocols
  • Dipeptidyl-Peptidase IV Inhibitors
  • Psoriasis
  • Sitagliptin Phosphate
  • Ultraviolet Therapy

abstract

  • We report the design, fabrication, and implementation of a device to culture rat hippocampal neurons guided by arrays of cell-adhesive biopolymers on traditional cell culture substrates. These guided arrays of cells are shown to permit live-imaging of mitochondrial transport through the cell axon. We further report the development of a microfluidic device to deliver solutes to discrete sections of rat hippocampal neurons with spatial and temporal resolution. © 2009 CBMS.

publication date

  • January 2009

Research

keywords

  • Conference Paper

Additional Document Info

start page

  • 481

end page

  • 483