Dichotomous effects of chronic intermittent hypoxia on focal cerebral ischemic injury Academic Article uri icon

Overview

MeSH Major

  • Cerebrovascular Circulation
  • Hypoxia
  • Infarction, Middle Cerebral Artery
  • Mitochondria

abstract

  • The influence of CIH on the ischemic brain is dichotomous and can be attributed, in part, to changes in the mitochondrial susceptibility to injury. The findings highlight a previously unappreciated complexity in the effect of CIH on the brain, which needs to be considered in evaluating the neurological effect of conditions associated with cyclic hypoxia.

publication date

  • January 2014

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC4006286

Digital Object Identifier (DOI)

  • 10.1161/STROKEAHA.114.004816

PubMed ID

  • 24713530

Additional Document Info

start page

  • 1460

end page

  • 7

volume

  • 45

number

  • 5