Integrated next-generation sequencing and avatar mouse models for personalized cancer treatment Academic Article uri icon

Overview

MeSH Major

  • High-Throughput Nucleotide Sequencing
  • Molecular Targeted Therapy
  • Neoplasms
  • Precision Medicine

abstract

  • The use of full genomic analysis for cancer care is encouraging but presents important challenges that will need to be solved for broad clinical application. Avatar models are a promising investigational platform for therapeutic decision making. While limitations still exist, this strategy should be further tested.

publication date

  • May 2014

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC4322867

Digital Object Identifier (DOI)

  • 10.1158/1078-0432.CCR-13-3047

PubMed ID

  • 24634382

Additional Document Info

start page

  • 2476

end page

  • 84

volume

  • 20

number

  • 9