Pharmacokinetics-based integration of multiple doses of intravenous pegaspargase in a pediatric regimen for adults with newly diagnosed acute lymphoblastic leukemia Academic Article uri icon

Overview

MeSH Major

  • Antineoplastic Combined Chemotherapy Protocols
  • Asparaginase
  • Polyethylene Glycols
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma

abstract

  • Our dose and schedule of pegaspargase, based on its pharmacokinetics, and our detailed toxicity profile could be applied for safer adaptation of pediatric ALL protocols in adults.

publication date

  • March 20, 2014

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1200/JCO.2013.50.2708

PubMed ID

  • 24516026

Additional Document Info

start page

  • 905

end page

  • 11

volume

  • 32

number

  • 9