Interstitial lung disease: NHLBI Workshop on the Primary Prevention of Chronic Lung Diseases. Review uri icon

Overview

MeSH

  • Chronic Disease
  • Humans
  • United States

MeSH Major

  • Congresses as Topic
  • Lung Diseases, Interstitial
  • National Heart, Lung, and Blood Institute (U.S.)
  • Primary Prevention

abstract

  • Population-based, longitudinal studies spanning decades linking risk factors in childhood, adolescence and early adulthood to incident clinical interstitial lung disease (ILD) events in late adulthood have not been performed. In addition, no observational or randomized clinical trials have been conducted; therefore, there is presently no evidence to support the notion that reduction of risk factor levels in early life prevents ILD events in adult life. Primary prevention strategies are host-directed interventions designed to modify adverse risk factors (i.e., smoking) with the goal of preventing the development of ILD, whereas primordial prevention for ILD can be defined as the elimination of external risk factors (i.e., environmental pollutants). As no ILD primary prevention studies have been previously conducted, we propose that research studies that promote implementation of primary prevention strategies could, over time, make a subset of ILD preventable. Herein, we provide a number of initial steps required for the future implementation of prevention strategies; this statement discusses the rationale and available evidence that support potential opportunities for primordial and primary prevention, as well as fertile areas for future research of preventive intervention in ILD.

publication date

  • April 2014

has subject area

  • Chronic Disease
  • Congresses as Topic
  • Humans
  • Lung Diseases, Interstitial
  • National Heart, Lung, and Blood Institute (U.S.)
  • Primary Prevention
  • United States

Research

keywords

  • Journal Article
  • Review

Identity

Language

  • eng

PubMed Central ID

  • PMC4112506

Digital Object Identifier (DOI)

  • 10.1513/AnnalsATS.201312-429LD

PubMed ID

  • 24754826

Additional Document Info

start page

  • S169

end page

  • S177

volume

  • 11 Suppl 3