Chemokines and chemokine receptors required for optimal responses to anticancer chemotherapy Academic Article uri icon

Overview

MeSH Major

  • Antigens, Differentiation
  • Calreticulin
  • Cell Cycle Proteins
  • Protein Phosphatase 1

abstract

  • Depending on tumor type, stage and immunological contexture, the inhibition of chemokines or their receptors may yield positive or deleterious effects on disease progression. We have recently demonstrated in several murine models of anthracycline-based chemotherapy that the inhibition of chemokine (C-C motif) ligand 2 (CCL2) or chemokine (C-C motif) receptor 2 (CCR2) may impair the elicitation of anticancer immune responses that contribute to therapeutic success.

publication date

  • January 2014

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC4008453

Digital Object Identifier (DOI)

  • 10.4161/onci.27663

PubMed ID

  • 24800170

Additional Document Info

start page

  • e27663

volume

  • 3

number

  • 1